Pengaruh Stimulus Dingin terhadap Tekanan Darah: Studi Cold Pressor Test pada Mahasiswa Kedokteran Universitas Tarumanagara Angkatan 2022
DOI:
https://doi.org/10.55606/klinik.v3i3.4394Keywords:
Cold Pressor Test, systolic blood pressure, diastolic blood pressureAbstract
The Cold Pressor Test (CPT) is a non-invasive method used to evaluate sympathetic nervous system reactivity to cold-induced stress. An exaggerated blood pressure response to CPT may indicate a predisposition to cardiovascular dysregulation.This study aimed to determine the effect of the Cold Pressor Test on blood pressure among medical students. A quasi-experimental design was employed, involving 74 medical students from the 2022 cohort at Tarumanagara University, who were divided into test and control groups. Systolic and diastolic blood pressures were measured before and after the intervention. Data were analyzed using the paired t-test or Wilcoxon signed-rank test, depending on data distribution. Results: The findings showed no statistically significant differences in systolic or diastolic blood pressure before and after the CPT in either group (p > 0.05). Conclusion: The Cold Pressor Test did not cause significant changes in blood pressure among the medical students studied
References
Hada, S., Amatya, S., & Shrestha, R. K. (2016). Cold pressor test in borderline hypertensive university students. Kathmandu University Medical Journal, 14(56), 337–341.
Hall, J. E., & Guyton, A. C. (2021). Textbook of medical physiology (14th ed., pp. 217–219). Elsevier.
Han, Y., Du, J., Wang, J., Liu, B., Yan, Y. L., Deng, S. B., Zou, Y., Jing, X. D., Du, J. L., Liu, Y. J., & She, Q. (2022). Cold pressor test in primary hypertension: A cross-sectional study. Frontiers in Cardiovascular Medicine, 9, 860322. https://doi.org/10.3389/fcvm.2022.860322
Lamotte, G., Boes, C. J., Low, P. A., & Coon, E. A. (2021). The expanding role of the cold pressor test: A brief history. Clinical Autonomic Research, 31(2), 153–155. https://doi.org/10.1007/s10286-021-00796-4
Matthews, K. A., Katholi, C. R., McCreath, H., Whooley, M. A., Williams, D. R., Zhu, S., & Markovitz, J. H. (2004). Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA study. Circulation, 110(1), 74–78. https://doi.org/10.1161/01.CIR.0000133415.37578.E4
Meher, M., Pradhan, S., & Pradhan, S. R. (2023). Risk factors associated with hypertension in young adults: A systematic review. Cureus, 15(4), e37467. https://doi.org/10.7759/cureus.37467
Mythri, G., & Shireen, S. Q. (2018). Effect of cold pressor test on blood pressure in normotensives and hypertensives. National Journal of Physiology, Pharmacy and Pharmacology, 8(2), 177–181. http://dx.doi.org/10.5455/njppp.2018.8.0010728417082017001
Pandarbale, S. S., Nerkar, Y. P., & Malnekar, S. R. (2020). Effect of cold pressor test (CPT) on pulse rate and blood pressure amongst individuals with and without family history of hypertension. Journal of Evolution of Medical and Dental Sciences, 9(32), 2253–2256. https://doi.org/10.14260/jemds/2020/488
Pouwels, S., Van Genderen, M. E., Kreeftenberg, H. G., Ribeiro, R., Parmar, C., Topal, B., Celik, A., & Ugale, S. (2019). Utility of the cold pressor test to predict future cardiovascular events. Expert Review of Cardiovascular Therapy, 17(4), 305–318. https://doi.org/10.1080/14779072.2019.1598262
Sherwood, L. (2016). Human physiology: From cells to systems (9th ed., pp. 417–419). Cengage Learning.
Tomitani, N., Kanegae, H., & Kario, K. (2023). The effect of psychological stress and physical activity on ambulatory blood pressure variability detected by a multisensor ambulatory blood pressure monitoring device. Hypertension Research, 46(4), 916–921. https://doi.org/10.1038/s41440-022-01123-8
Watts, A. C., Naylor, L. A., Jensen, B. T., & Holmstrup, M. E. (2023). The impact of the Cold Pressor Test on inter-arm differences in blood pressure. International Journal of Exercise Science, 16(2), 875–884. https://doi.org/10.70252/GCBS3322
World Health Organization. (2023). Hypertension. https://www.who.int/news-room/fact-sheets/detail/hypertension
Zhang, M., Zhao, Q., Mills, K. T., Chen, J., Li, J., Cao, J., Gu, D., & He, J. (2013). Factors associated with blood pressure response to the cold pressor test: The GenSalt Study. American Journal of Hypertension, 26(9), 1132–1139. https://doi.org/10.1093/ajh/hpt075
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