Hubungan Kepatuhan Minum Obat terhadap Kualitas Hidup Pasien TB Paru di Rumah Sakit Budiasih
DOI:
https://doi.org/10.55606/klinik.v4i1.5129Keywords:
Adherence, MMAS-8, Tuberculosis (TB), WHOQOL-BREFAbstract
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, which generally attacks the lungs, although it can affect other organs. The World Health Organization (WHO) identifies TB as a leading cause of death worldwide, with millions of new cases each year. A crucial factor in TB treatment is patient compliance with treatment, as irregular treatment can lead to drug resistance and weaken the patient's condition. This study aims to determine the relationship between medication adherence and quality of life of pulmonary TB patients at Budiasih Hospital. The method used is an observational study with a cross-sectional approach. The study population was pulmonary TB patients, with a sample consisting of patients who met the inclusion and exclusion criteria. The questionnaires used included the MMAS-8 to measure compliance and the WHOQOL-BREF 1996 to measure quality of life. Data analysis was performed using the chi-square test to examine the relationship between variables. The second variable is said to have a significant relationship if the p-value is less than 0.05. The results showed that the fulfillment of drinking water for pulmonary TB patients was categorized as high at 54.0%, and the quality of life of most pulmonary TB patients was categorized as moderate at 69.8%. The analysis also revealed a significant relationship between medication adherence and the quality of life of pulmonary TB patients at Budiasih Hospital, with a p value of 0.000 (p<0.05). This study provides important insights into the importance of implementing treatment to improve the quality of life for pulmonary TB patients. In addition, this study also showed that although the majority of patients had a good level of medication fulfillment, the majority of patients still experienced a moderate quality of life.
References
Abrori, I., Abrori, I., & Ahmad, R. A. (2018). Kualitas hidup penderita tuberkulosis resisten obat di Kabupaten Banyumas. Berita Kedokteran Masyarakat, 34(2), 55–61. https://journal.ugm.ac.id/bkm/article/view/26616
Amalia, A., et al. (2022). Analisis hubungan tingkat kepatuhan minum obat antituberkulosis terhadap kualitas hidup pasien tuberkulosis paru. JIM: Jurnal Ilmiah Mahaganesha, 1(2), 67–74. https://ojs.farmasimahaganesha.ac.id/index.php/JIM/article/view/111
Dewi, B. A. S., et al. (2022). Kecemasan pada penderita tuberculosis. Jurnal Kesehatan, 11(2), 92–95. https://doi.org/10.46815/jk.v11i2.108
Esse, P. P., Jufri, & Miftahul, A. (2020). Gambaran kualitas hidup pada pasien tuberkulosis paru (TB paru) di Balai Besar Kesehatan Paru Masyarakat (BBKPM) Makassar. Jurnal Mitrasehat, 10(1), 168–177. https://doi.org/10.51171/jms.v10i1.134
Fazriana, E. (2025). Hubungan antara dukungan sosial keluarga dengan resiliensi penderita TB paru. 2(1), 9–11.
Fistalia, D. I. A. A., Octavia, D. R., & Sahara, S. B. (2023). Hubungan kepatuhan minum obat dengan kualitas hidup pasien tuberkulosis di Puskesmas Kabupaten Lamongan Dewi. Journal of Pharmacy and Science, 8(2), 179–185. http://www.ejournal.akfarsurabaya.ac.id/index.php/jps/article/view/363/234
Fortuna, T. A., et al. (2022). Studi penggunaan obat anti tuberkulosis (OAT) tahap lanjutan pada pasien baru BTA positif. Pharmacon: Jurnal Farmasi Indonesia, 19(1), 62–71. https://doi.org/10.23917/pharmacon.v19i1.17907
Gunawan, A. R. S., Simbolon, R. L., & Fauzia, D. (2017). Faktor-faktor yang mempengaruhi tingkat kepatuhan pasien terhadap pengobatan tuberkulosis paru di lima puskesmas se-kota Pekanbaru. Jurnal Online Mahasiswa Fakultas Kedokteran Universitas Riau, 4(2), 1–20. https://jom.unri.ac.id/index.php/JOMFDOK/article/view/15495/15037
Herdiman, H., Rahman, D., & Lindayani, L. (2020). Gambaran kepatuhan minum pada pasien TB di wilayah Puskesmas Kecamatan Cimaung. Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal), 6(1), 59–63. https://doi.org/10.33755/jkk.v6i1.175
Lambanaung, P. W., Asrifuddin, A., & Sekeon, S. A. S. (2019). Faktor-faktor yang berhubungan dengan upaya pencegahan penyakit TB paru pada masyarakat di wilayah kerja Puskesmas Girian Weru Kota Bitung. Jurnal Kesmas, 8(6), 395–402.
Mientarini, E. I., Sudarmanto, Y., & Hasan, M. (2018). Hubungan pengetahuan dan sikap terhadap kepatuhan minum obat pasien tuberkulosis paru fase lanjutan di Kecamatan Umbulsari Jember. Ikesma, 14(1), 11. https://doi.org/10.19184/ikesma.v14i1.10401
Papeo, D. R. P., Immaculata, M., & Rukmawati, I. (2021). Hubungan antara kepatuhan minum obat (MMAS-8) dan kualitas hidup (WHOQOL-BREF) penderita tuberkulosis di Puskesmas di Kota Bandung. Indonesian Journal of Pharmaceutical Education, 1(2), 86–97. https://doi.org/10.37311/ijpe.v1i2.11143
Permatasari, I. E. S. S. F. S., & Ana, N. (2020). Kepatuhan konsumsi obat pasien hipertensi dan pengukuran serta cara meningkatkan kepatuhan. Graniti Anggota IKAPI, 1–85.
Putra, O. N., et al. (2022). Evaluasi kualitas hidup pasien tuberkulosis paru menggunakan instrumen Short Form-36. Jurnal Ilmiah Farmako Bahari, 13(1), 1. https://doi.org/10.52434/jfb.v13i1.1398
Rochjana, A. U. H., & Laeman, S. A. (2024). Profil penggunaan obat anti tuberkulosis paru di instalasi farmasi rawat jalan BPJS Rumah Sakit “X” Jakarta Pusat periode Januari-Desember 2022. Indonesian Journal of Health Science, 4(4), 398–405. https://doi.org/10.54957/ijhs.v4i4.950
Setyowat, I., Aini, D. N., & Retnaningsih, D. (2019). Faktor-faktor yang mempengaruhi kepatuhan minum obat pada penderita TB paru di RSI Sultan Agung Semarang. Jurnal Kesehatan, 46–56.
Ternate, K., et al. (2015). Hubungan kualitas lingkungan fisik rumah dengan Puskesmas Perawatan Siko Kecamatan Ternate Utara, 3.
Vahedi, S. (2010). World Health Organization Quality-Of-Life Scale (WHOQOL-BREF): Analyses of their item response theory properties based on the graded responses model. Iranian Journal of Psychiatry, 5(4), 140–153. https://www.ncbi.nlm.nih.gov/pubmed/22952508 https://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC3395923
Widyastuti, S. D., Riyanto, R., & Fauzi, M. (2018). Gambaran epidemiologi penyakit tuberkulosis paru (TB Paru) di Kabupaten Indramayu. Care: Jurnal Ilmiah Ilmu Kesehatan, 6(2), 102. https://doi.org/10.33366/cr.v6i2.911
World Health Organization. (1996). WHOQOL-BREF: Introduction, administration, scoring and generic version of the assessment: Field trial version, December. World Health Organization, 1–16.
World Health Organization. (2022). WHO consolidated guidelines on tuberculosis. Module 5: Management of tuberculosis in children and adolescents. https://www.who.int/publications/i/item/9789240046764
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jurnal Ilmiah Kedokteran dan Kesehatan

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.